Toxicity is extremely rare following administration of recommended dose. Nevertheless, massive overdose of acetaminophen may adversely affect the liver of some people and signs and symptoms of overdose may be delayed for up to 1 week following ingestion. Nevertheless, liver damage is largely reversible if the patient is treated early, thus prompt medical attention is essential in all cases of suspected overdose even if there is no sign or symptom. Acetaminophen overdose may cause liver failure.
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